Department of Physiology

INTRODUCTION

The Department of Physiology began in 2003, in conjunction with the establishment of the Medical Faculty in UiTM. Initially, the discipline was anchored by a professor of physiology and its members expanded overtime in line with the increase in student intake. Today, the discipline has 10 academicians.

Physiology generally is the study of the body functions and is also considered to be one of the major scientific foundations in the study of medicine and health sciences. The academicians in the discipline therefore play an important role in the Faculty of Medicine in ensuring that the medical students get a sound foundation in physiology before they proceed into the clinical years. Besides teaching, the staff is also actively involved in research.

Research has become an important priority in addition to teaching within the discipline and its research strength centres around areas in reproductive, endocrine, cardiovascular physiology, physiology and pathophysiology of leptin, and neurophysiology. Most of the research is funded through the FRGS and ERGS although a few of the projects are also funded by the University internal grants. Research work of the staff has been published in numerous indexed, peer-reviewed journals.

Members of Physiology Department

noraliza
Assoc. Prof. Dr. Nuraliza Abdul Satar
B.Biomed.Sc(UKM),PhD(UKM)
harbinder
Prof. Dr. Harbinder Jeet Singh A/L Gurcharan Singh
B.Sc.Biological Sciences(Manchester),
PhD(Manchester)
prof hamim
Prof. Dr. Mohd Hamim Rajikin
B.Sc.Biology(UKM),
MSc(UM), PhD(UM)
dama
Dr. Damayanthi A/P Durairajanayagam
B.Biomed.Sc(UKM),
Phd(UKM)
rosfaizah
Dr. Rosfaiizah Siran
MBBCHBAO(Ireland),
PhD(USM)
azean
Dr. Noor Azean Anis Abd Aziz
B.Med.Sc(UPM),
MBBS(UPM), PhD(UiTM)
shikintambeh
Dr. Norashikin Mohd Tambeh
MBBS(UM),
MSc(UiTM)
yuhaniza
Dr. Yuhaniza Shafinie Kamsani
B.Med.Sc.Tech(UM),
PhD(UiTM)
effendi
Dr. Effendi Ibrahim
B.Sc(UKM),MSc(UKM),
PhD(London)
nasibah
Dr. Nasibah Azme
MB BCh(Al-Azhar),
MSc(UiTM)

RESEARCH PROJECTS

ASSOC. PROF. DR. NURALIZA BINTI ABDUL SATAR.

Sirt 1 Gene Expression In Aging Mouse Embryos Following Tocotrienol Supplementation. 600-RMI/Dana 5/3/Psf (26/2014)

FRGS Project Title 'Protective Role Of Tocotrienol On The Expression Of Dna Repair Genes In Developing Embryos Of Corticosterone-Induced Oxidative Stress Mice" 600-IRMI/GIP 5/3 (0049/2016)

 

PROF. DR. HARBINDAR JEET SINGH

Mechanisms of anti-hypertensive effects of standardised water and ethanol extracts of ficus deltoid (kunsleri, bilobata and terengganuesis)  in spontaneously hypertensive rats. 100-RMI/MOA 16/6/2 (1/2015)

Role of marinobufagenin and ACE2 activation in the pathogenesis of leptin-induced hypertension and proteinuria of pregnant Sprague-Dawley rats. (FRGS)

Interactions between Adipokines, ACE2 and Markers of Endothelial Activation in Human Coronary Artery Endothelial Cells. (ERGS)

 

Dr. DAMAYANTHI A/P DURAIRAJANAYAGAM

Determination Of Pathways Responsible For Sperm Dna Damage Following Leptin Treatment Of Spermatogonia, Sertoli Cells And Leydig Cells In Vitro. 600-RMI/FRGS 5/3 (0011/2016).

 

DR. ROSFAIIZAH SIRAN

Neuroprotection via Autophagy Modulation by Neurosteroids with Therapeutic Hypothermia in Hypoxic Ischaemic Cultured Neuronal Cells. 600-RMI/RACE 16/6/2(12/2013)

The Effect Of Hypothermia And Progesterone On Reducing Glutamate Toxicity Via Glutamate Transporter – 1 (GLT-1) Protein in Astrocytes. 600-RMI/Dana 5/3/Psf (26/2015)

 

Dr. YUHANIZA SHAFINIE KAMSANI

Effect Of Gamma-Tocotrienol On The Cytoskeletal Structure Of Pre-Implantation Embryos In Mice Treated With Nicotine. 600-RMI/RAGS 5/3 (44/2014)

The Correct Use Of Seatbelt In Pregnancy : Educating The Public. 100-IRMI/PRI 16/6/2 (0028/2016)           

 

DR. SITI NORASHIKIN MOHD TAMBEH

Effects Of Aloe Emodin Supplementation On Type II Collagen And Glycosaminoglycan (GAG) Level In Chondroctytes Of Osteoarthritic Patients. 600-RMI/RAGS 5/3 (68/2015)

 

DR. NASIBAH BINTI AZME . Delay In Oocyte Aging In Mice By The Antioxidant Tocotrienol. 600-RMI/Dana 5/3/Psf (2/2015)

 

PUBLICATIONS

Almabhouh FA, Osman K, Siti Fatimah I, Sergey G, Gnanou J Singh HJ (2015) Effects of leptin on sperm count and morphology in Sprague-Dawley rats and their reversibility following a 6-week recovery period. Andrologia 47:751-758

Brinnell Caszo, Zanariah Awang, Justin Gnanou, Harbindarjeet Singh (2015) The presence of littermate during measurement of blood pressure reduces the acclimatization time in conscious rats.Asian Journal of Pharmaceutical and Clinical Research  8(2): 151-153

Khalil Wjidan, Hisham Saleh, Effendi Ibrahim, Justin Gnanou, Harbindarjeet Singh (2015) Dysregulation of Glucose Homeostasis Following Chronic Exogenous Administration of Leptin in Healthy Sprague-Dawley Rats.Journal of Clinical and Diagnostic Research  9(12): OF06-OF09

Dhillon HK, Zain AZM, Fatt QK, Singh HJ, Kaur G and Nordin RB  (2016)  Female Urinary Incontinence: A Study Protocol Using the Malay QUID in Selangor, Malaysia. J Women's Health Care 5:6 DOI: 10.4172/2167-0420.1000338 (In press).

Dhillon HK, Zain AZM, Fatt QK, Singh HJ, Kaur G and Nordin RB  (2016)  Prevalence and Risk Factors of Urinary Incontinence and its Impact on the Quality of Life and Treatment Seeking Behaviour among Malaysian Women: A Review.J Women's Health Care 5:6 DOI: 10.4172/2167-0420.1000337 (In press)

Almabhouh FA, Khairul Osman, Siti Fatimah I, Sergey Gupalo, Justin Gnanou,  Effendi Ibrahim, HJ Singh (2016):  Melatonin ameliorates Leptin induced adverse effects on sperm. Asian Journal of Andrology 2016 (18), 1–8

Brinnell Caszo, Azdayanti Muslim, Zanariah Awang, Effat Omar, Effendi Ibrahim, Harbindar Jeet Singh (2017)  The effects of leptin administration on renal function in spontaneously hypertensive rats.  Asian Journal of Pharmaceutical and Clinical Sciences (In press)

Fayez A Almabhouh and HJ Singh (2017) Leptin adversely affects the transition of Histone-to-protamine during spermatogenesis in Sprague-Dawley rats.  IUG Journal of Natural Sciences Vol 25 No.2 (In press)

Almabhouh FA and Singh HJ (2017) Adverse effects of leptin on histone-to-protamine transition during spermatogenesis are prevented by melatonin in Sprague-Dawley rats. Andrologia (In press)

Norerlyda H, Fathimah M & Nuraliza AS. 2015. The effect of tocotrienol supplementation on plasmaestradiol levels and quality of embryos in aging ice. Malaysian Journal of Microscopy. 11:32-38 (Scopus indexed)

Kamsani, Y.S. and Rajikin, M.H. (2017). Review : tocotrienols on oocytes of nicotine-induced animals. Journal of Clinical and Health Sciences (Galley Proof).

Hamirah, N.K., Kamsani, Y.S., Nor-Ashikin, M.N.K., Ab-Rahim, S. & Rajikin, M.H. (2017). Effects of nicotine and tocotrienol-rich fraction supplementation on cytoskeletal structures of murine pre-implantation embryos. Medical Science Monitor (submitted to Medical Science Monitor).

 

CONTACT

Assoc. Prof. Dr. Nuraliza Abdul Satar (Head of Department)

Tel : +60361267227

Email: nuraliza064@salam.uitm.edu.my

Address:

          Faculty of Medicine,

          Universiti Teknologi MARA (UiTM)

          Sungai Buloh Campus,

          Jalan Hospital, 47000 Sungai Buloh,

          Selangor Darul Ehsan,

          Malaysia