Department of Pharmacology

INTRODUCTION

The department of Pharmacology started with only one Professor in 2004, with the addition of another Professor and a Trainee Lecturer in 2005. Despite this, the discipline has been heavily involved in the initial development and later modification of the Faculty’s unique curriculum. We also played our part in helping the Faculty achieve accreditation by the Malaysian Qualification Agency in 2008.

Since then, discipline members have come and gone but the level of commitment of the discipline towards providing quality in teaching and learning remained high. To date, we have a dedicated set of lecturers who are focused in achieving the discipline’s and the Faculty’s mission and vision for the future.

Members of discipline have taken lead in key research areas and postgraduate training. The members are holding several internal and external grants and are supervising Master and PhD students. One of the initiative taken by the discipline is to set up Neuroscience Lab in the faculty. The Neuroscience lab is very well equipped and can be considered one of the best in Malaysia.

Members of Pharmacology Department

anna
Assoc Prof Dr Anna Krasilnikova
MBBS(Volgograd),
PhD(Volgograd)
renu
Prof. Dr. Renu Agarwal
MBBS(India),MSc(USM),
PhD(Delhi)
igor
Assoc. Prof. Dr. Igor N. Iezhitsa
M.Sc.Bology(Russia),
PhD(Volgograd)
hafiza
Dr Norhafiza Razali
MB, BCh, BAO(Ireland),
PhD(UiTM)
alimah
Dr Nurul Alimah Abdul Nasir
MBBS(UM),,
PhD(UiTM)
Huzaimi
Dr. Muhammad Huzaimi Haron
MBBCHBAO(Indonesia),
MSc(UM),PhD(UK)
fahitah
Dr. Noor Fahitah Binti Abu Hanipah
MBBS
norsyafika
Dr. Siti Norsyafika Binti Kamarudin
MBBS
norasikin
Dr. Norasikin Ab Azis
MD(Indonesia)

RESEARCH PROJECTS

Assoc Prof Dr Renu Agarwal

Studies to elucidate suppression of TGF-ß2 as the mechanism of resveratrol-induced oculohypotension: In vivo and in vitro studies. Ministry of Education, Government of Malaysia, Top-Down FRGS: RM 127,000/-. 600-RMI/FRGS TD 5/3 (2/2015).

Elucidation of adenosine receptor signaling mechanisms involved in resveratrol-induced ocular hypotension: in vivo and in vitro studies. Ministry of Education, Government of Malaysia, under FRGS: RM 132,000/-.600-RMI/FRGS 5/3 (110/2014).

Effect of taurine against endothelin-1 induced retinal and optic nerve injury. Universiti Teknologi MARA under Bestari: RM 40000/- 600-IRMI/DANA 5/3/BESTARI (006/2017).

Assoc Prof Dr Igor Iezhitsa

Principle BDNF-Related Anti-Neurodegenerative Mechanism and Histopathological Basis of Behavioral Changes In Amyloid-Induced Neurodegenerative Diseases; 600-RMI/FRGS 5/3 (111/2014); Ministry of Education, Government of Malaysia; (2014-2017)

Study to investigate mechanism of neuroprotection by taurine against NMDA-induced retinal ganglion cell death; 600-IRMI/MyRA 5/3/BESTARI (004/2017); Universiti Teknologi MARA , (2014-2017)

Assoc Prof Dr Anna Krasilnikova

Anti-remodeling mechanism of renin-angiotensin system inhibitors on trabecular meshwork: Role of TGFβ. Ministry of Education, Government of Malaysia, under FRGS: RM 184,160/-. 600-RMI/FRGS 5/3 (24/2014)

Dr. Norhafiza Razali

Involvement of Adenosine Receptors in Resveratrol-induced MMP Secretion (Research Entity Initiative, Universiti Teknologi MARA):RM 30,000. 600-IRMI/DANA 5/3/REI (0007/2016)

 

 

PUBLICATIONS

Norhafiza Razali, Renu Agarwal, Puneet Agarwal, Marina Y Kapitonovaa, Methil Kannan Kutty, Alexey Smirnov, Nor Salmah Bakar, Nafeeza M. Ismail. Anterior and posterior segment changes in rat eyes with chronic steroid administration and their responsiveness to antiglaucoma drugs. European Journal of Pharmacology. 2015; 749:73–80. Impact factor 2.73

Norhafiza Razali, Renu Agarwal, Puneet Agarwal, Sunil Kumar, Minaketan Tripathy, Sushil Vasudevan, Jonathan G Crowston, Nafeeza M Ismail. Role of adenosine receptors in resveratrol-induced IOP lowering in rats with steroid-induced ocular hypertension. Clin Exp Ophthalmol. 2015; 43(1): 54-66. Impact factor 2.55

Puneet Agarwal, Aqil Mohammad Daher, Renu Agarwal. Aqueous humor TGF-β2 levels in patients with open-angle glaucoma: A meta-analysis. Molecular Vision 2015; 21:612-620. Impact factor 2.11

Renu Agarwal, Nafeeza Mohd Ismail. Regenerative Medicine: A promising approach in overcoming diabetes as an increasing economic health burden. Journal of Emerging Economies and Islamic Research. 2015; 3(2):1-5.

Nurul Alimah Abdul Nasir, Puneet Agarwal, Renu Agarwal, Igor Iezhitsa, Renad Alyautdin, Natalia N. Nukolova, Vladimir P. Chekhonin, Nafeeza Mohd Ismail. Intraocular distribution of topically applied hydrophilic and lipophilic substances in rat eyes. Drug Delivery. 2016 Oct;23(8):2765-2771. Impact factor 4.84

Razali N, Agarwal R, Agarwal P, Tripathy M, Kapitonova MY, Kutty MK, Smirnov A, Khalid Z, Ismail NM. Topical trans-resveratrol ameliorates steroid-induced anterior and posterior segment changes in rats. Exp Eye Res. 2016; 143, 9-16. Impact factor 3.15

NNN Arfuzir, L Lambuk, AJA Jafri, R Agarwal, I Iezhitsa, S Sidek, P Agarwal, NS Bakar, MK Kutty, AP Md Yusof, A Krasilnikova, A Spasov, A Ozerov, N Mohd Ismail. Protective effect of magnesium acetyltaurate against endothelin-induced retinal and optic nerve injury. Neuroscience. 2016; 325:153-164. Impact factor 3.23

Dongare S, Gupta SK, Mathur R, Saxena R, Mathur S, Agarwal R, Nag TC, Srivastava S, Kumar P. Zingiber officinale attenuates retinal microvascular changes in diabetic rats via anti-inflammatory and antiangiogenic mechanisms. Molecular Vision 2016; 22:599-609. Impact factor 2.11

Renu Agarwal, Nafeeza Mohd Ismail. Students' Perception of Teaching Methods in Pharmacology in a Malaysian Medical School. Journal of Clinical and health Science. 2016; 1(1):16-21.

Iezhitsa I, Agarwal R, Saad SD, Zakaria FK, Agarwal P, Krasilnikova A, Rahman TH, Rozali KN, Spasov A, Ozerov A, Alyautdin R, Ismail NM. Mechanism of the anticataract effect of liposomal MgT in galactose-fed rats. Mol Vis. 2016 Jul 10;22:734-47. Impact factor 2.11

Nurul Suriane Abu Hassan, Nurul Ainsya Bakry, Renu Agarwal, Anna Krasilnikova, Siti Hamimah Sheikh Abdul Kadir, Igor Iezhitsa and Nafeeza Mohd Ismail. The Effect of Dexamethasone on Synthesis of Collagen, Fibronectin and α-smooth Muscle Actin in Cultured Human Trabecular Meshwork Cells. Ind J Physiol Pharmacol. 2016; 60(4):352-363. Impact factor 0.599

Lambuk L, Jafri AJ, Arfuzir NN, Iezhitsa I, Agarwal R, Rozali KN, Agarwal P, Bakar NS, Kutty MK, Yusof AP, Krasilnikova A, Spasov A, Ozerov A, Ismail NM. Neuroprotective Effect of Magnesium Acetyltaurate Against NMDA-Induced Excitotoxicity in Rat Retina. Neurotox Res. 2017 Jan;31(1):31-45. Impact factor 3.14

Azliana Jusnida Ahmad Jafri, Natasha Najwa Nor Arfuzir, Lidawani Lambuk, Igor Iezhitsa, Renu Agarwal, Puneet Agarwal, Norhafiza Razali, Anna Krasilnikova, Maria Kharitonova, Vasily Demidov, Evgeny Serebryansky, Anatoly Skalny, Alexander Spasov, Ahmad Pauzi Md. Yusof, Nafeeza Mohd Ismail. Protective effect of magnesium acetyltaurate against NMDA-induced retinal damage involves restoration of minerals and trace elements homeostasis. J Trace Elem Med Biol. 2017 Jan;39:147-154. Impact factor 2.55

Renu Agarwal, Puneet Agarwal. Targeting ECM remodeling in disease: could resveratrol be a potential candidate? Experimental Biology and Medicine. 2017 Feb;242(4):374-383. Impact factor 2.54

Invited review: Renu Agarwal, Puneet Agarwal. Rodent models of glaucoma. Expert Opinion on Drug Discovery. 2017 Mar;12(3):261-270. Impact factor 3.54

Abdul Nasir NA, Agarwal R, Sheikh Abdul Kadir SH, Vasudevan S, Tripathy M, Iezhitsa I, Mohammad Daher A, Ibrahim MI, Mohd Ismail N. Reduction of oxidative-nitrosative stress underlies anticataract effect of topically applied tocotrienol in streptozotocin-induced diabetic rats. PLoS One. 2017 Mar 28;12(3):e0174542. Impact factor 4.41

Normie Aida Mohd Nasir, Renu Agarwal, Anna Krasilnikova, Siti Hamimah Abdul Kadir, Igor Iezhitsa, Ahmad Bakhtiar Bin Md Radzi, Farhan Bin Hamdan, and  Nafeeza Mohd Ismail. The Effect of Trans-Resveratrol on The Viability of Human Trabecular Meshwork Cells. Res J Pharmaceutical, Biol Chem Sci. 2017; 8(3): 88-95. Scopus

Anastasia A. Zheltova, Maria V. Kharitonova, Igor N. Iezhitsa, Alexander A. Spasov, Magnesium deficiency and oxidative stress: an update. BioMedicine (Netherlands) 2016, 6(4), 8-14 (Scopus)

Anastasia A. Zheltova, Maria V. Kharitonova, Igor N. Iezhitsa, Eugeny P. Serebryansky, Oleg Y. Evsyukov, Alexander A. Spasov, Anatoly V. Skalny. Low magnesium diet alters distribution of macroelements and trace elements in tissues and organs of female rats. Journal of Trace Elements in Medicine and Biology 2017; 39: 36-42 Impact factor 3.23

Kharitonova M., Iezhitsa I., Zheltova A., Ozerov A., Spasov A., Skalny A. Comparative angioprotective effects of magnesium compounds. Journal of Trace Elements in Medicine and Biology. 2015 Jan;29:227-234.. Impact factor 3.23

 

 

CONTACT

Assoc Prof Dr Anna Krasilnikova (Head of Department)

Tel : 03  6126 7196

Email:krasilnikova_anna@salam.uitm.edu.my

Address:

          Faculty of Medicine,

          Universiti Teknologi MARA (UiTM)

          Sungai Buloh Campus,

          Jalan Hospital, 47000 Sungai Buloh,

          Selangor Darul Ehsan,

          Malaysia